John Pavlidis, president and CEO of VytronUS, has built a strong resume leading and selling Medtech start-ups. Now the self-described engineering “nerd” is leading VytronUS, a start-up combining the powers of imaging, ablation, and robotics to create a powerful new tool that can elevate the precision in the electrophysiology lab. In this Medtech Talk Podcast, Pavlidis tells what lessons he learned jumping from a large company (Siemens) to serving as CEO of a small company. He also explains the great potential for VytronUS, which is developing a catheter-based endocardial ablation platform based on Low-Intensity Collimated Ultrasound (LICU). LICU can produce high-resolution maps of cardiac anatomy and deliver ablative energy without touching the tissue.